![]() ![]() ![]() In addition, patients with a metachronous MPC showed late survival disadvantage, while patients with a synchronous MPC showed early survival disadvantage. GC patients with either metachronous or synchronous MPC showed poorer survival than patients without MPC. Multivariate logistic regression analysis revealed that old age at the time of GC diagnosis (>60 years), early stage of GC (stage I and II), and multiplicity of GC at the time of gastrectomy were independent predictive factors for metachronous MPC. ![]() The most prevalent site of metachronous MPC was the colorectum (26.3%), followed by lung (23.7%) and liver (18.4%). Of these, 54.3% had a metachronous MPC, while 45.7% had a synchronous MPC. Results: The 5-year incidence of MPC was 2.5%. Methods: 3066 patients who underwent curative resection of GC were reviewed retrospectively, based on the clinical information and the medical record. The purpose of this study is to evaluate the clinicopathological features of MPC and to generate useful tools for the prediction of metachronous MPC following gastrectomy. Prediction of metachronous multiple primary cancers following the curative resection of gastric cancerĬhan Kim1,2, Hong Jae Chon1,2, Beodeul Kang1,2, Kiyeol Kim4, Hei-Cheul Jeung1,2,3, Hyun Cheol Chungīackground: Due to improved survival rate, gastric cancer (GC) patients have an increased risk of developing multiple primary cancer (MPC). ![]()
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